Myo-inositol and D-chiro-inositol are two of the most studied supplements for managing polycystic ovary syndrome (PCOS) and improving hormonal issues.

Research indicates they can improve insulin sensitivity, reduce metabolic symptoms, and enhance fertility in women with PCOS. When used in combination, particularly at a 40:1 ratio, these compounds show more significant benefits than individual supplementation.

Omega-3 fatty acids help balance hormones by reducing inflammation, which can otherwise lead to estrogen dominance and androgen deficiency.

For women with PCOS, omega-3s may help regulate menstrual cycles, lower testosterone levels, and reduce inflammation-related symptoms like acne. Additionally, omega-3 supplementation has shown promise in alleviating menstrual cramps by lowering prostaglandin levels, which are responsible for uterine contractions and pain

Diindolylmethane (DIM) improves estrogen metabolism, helping to balance hormones and potentially reducing symptoms of estrogen dominance such as PMS, breast tenderness, and hormonal headaches.

For women with PCOS, DIM supplementation helps regulate menstrual cycles, decrease testosterone levels, and alleviate symptoms like hirsutism and acne.

Vitamin D3 regulates enzymes involved in estrogen synthesis and metabolism, improving hormonal balance. For women with PCOS, vitamin D3 supplementation enhances insulin sensitivity, reduces hyperandrogenism, and helps regulate menstrual cycles.

Studies have shown that vitamin D3 can decrease serum testosterone levels while increasing folliculogenesis, which may improve fertility in PCOS patients. Additionally, vitamin D3 supplementation has been associated with reduced AMH levels in PCOS patients, suggesting a positive impact on ovarian function.

Magnesium glycinate is beneficial for hormonal balance and PCOS (Polycystic Ovary Syndrome) due to its multifaceted effects on the endocrine system and metabolism. It plays a crucial role in regulating sex hormones like estrogen and testosterone, as well as stress hormones like cortisol. For PCOS specifically, magnesium supplementation may help improve insulin sensitivity, glucose metabolism, and lipid profiles, addressing key metabolic issues associated with the condition.

Additionally, magnesium glycinate offers anti-inflammatory properties, potentially reduces anxiety, improves sleep quality, and may help prevent migraines - all of which can be beneficial for women with PCOS. The glycine component enhances magnesium absorption and provides a calming effect. While these benefits are promising, it's important to consult with a healthcare professional to determine the appropriate dosage, as individual needs may vary and more research is needed to fully understand the effects of magnesium glycinate on PCOS.

Zinc plays a crucial role in regulating insulin sensitivity and glucose metabolism, which is particularly important for women with PCOS who often experience insulin resistance.

Zinc supplementation has been shown to reduce hirsutism and hair loss in PCOS patients, potentially by blocking excess androgens. It may also help improve skin health by reducing acne severity. Additionally, zinc supports thyroid function, which is significant as women with PCOS are at higher risk for thyroid disorders. Some studies suggest that zinc supplementation can lower cholesterol levels and decrease inflammation in women with PCOS.